15. Freakonomics is a registered service mark of Renbud Radio, LLC. Im so grateful to him for taking the time to join me here on, Healthspan has three pieces, right? [8][9] By reducing the amount of carbohydrates we consume and by exercising, we reduce the amount of glucose were consuming and increase our muscle so that when we do consume glucose, our bodies have somewhere to put it. And we differentiate that form from the one that we evolved with by calling it nutritional ketosis. For all its successes, mainstream medicine has failed to make much progress against the diseases of aging that kill most people: heart disease, cancer, Alzheimers disease, and type 2 diabetes. I think once I was in medical school and I decided I wanted to become a surgeon, I just had this anxiety, which was, Well, what if you have to operate in the middle of the night and youre tired? So one of the things I started doing in my last year of medical school was, every Thursday night I would stay up, pull an all-nighter, stand at my desk, not allow myself to pee, and practice suturing on my desk in this model that I made that was supposed to resemble a human heart. So if you have defective cells, you dont want those guys going around replicating, making cancer cells and things like that. Physician. He is the host ofThe Drive, one of the most popular podcasts covering the topics of health and medicine. What was the failure of either policy or medicine that led nobody to be generating that knowledge? So, if we can stop eating a few hours before bedtime, well get better sleep, our bodies will process the glucose we consume, and we can avoid Type 2 diabetes. And you were like, Whats that? And I was like, Oh, I chew Nicorette gum. And you asked me if I was a smoker. Apparently Peter and his buddy Gary Taubes just love themselves some crappy pseudoscience. Ive never really experienced nicotine. The second thing I would say is: really do not consider sunk costs in your career. You went to McKinsey. That way, we can live lives that are both long and healthy! In addition to training at Johns Hopkins Hospital, Dr. Peter also spent two years at the National Institutes of Health as a surgical oncology fellow at the National Cancer Institute, where his research focused on immune-based therapies for melanoma. The Buddha said, To keep the body in good health is a duty otherwise we shall not be able to keep the mind strong and clear. And Tony Robbins said, The human body is the best picture of the human soul.. But what was it? And again fortunately, Olivias my oldest and shes 11. A SIXTEEN-ARTICLE POWERBOMB. And I was like, You know what? document.getElementById( "ak_js_3" ).setAttribute( "value", ( new Date() ).getTime() ); This field is for validation purposes and should be left unchanged. Ive known Peter for 10 years. I mean, I probably wish I had been a bit more introspective a bit sooner. He also receives speaking honorariums from organizations, including hospitals and health-related businesses, when he is asked to speak on longevity, metabolic-related topics, athletic performance, and his personal experience working in medicine. He attended Stanford University School of Medicine, where he received his M.D. So my guess is, theres some measure around helping them become better thinkers. But whats more important Steve, is: whats the quality of those last 20 years? How we are going about medicine the wrong way. And better? Where did this insecurity come from? And you say, I die.. @bariweiss. But its something I at least pay attention to now. Six feet versus two feet., And if you could now paint the boundary conditions of that universe with actual data, the next time a virus comes up, we would at least have boundary conditions to say, Oh, this virus looks most like this virus.. And at the time, what they said I dont know if they still say it was that if you just limit yourself to something like three hours of sleep, you get used to it and your body adjusts to it. Your podcasts are like a massive gift to humanity. And you would say, Peter, those seem really easy, and youd be right as a 37-year-old stud, but the point is most 60 year olds couldnt do them. Dr. Peter Attia. Wouldnt you like to live longer? But not too far behind it is cancer. And so when I decided to leave, my first thought was actually to go to business school, because I really missed doing quantitative problem-solving. Were living to reach older and older ages than ever before, which is great. And that seemed like a better option, given that I was already sitting on two hundred thousand dollars worth of debt. And we might have to take a closer look at your sleep habits. Part of the practice includes nutritional biochemistry, a field that deals with supplements. I dont know that its a substitute for the nighttime sleep, though. What things are attributing to bad sleeping patterns. On this Wikipedia the language links are at the top of the page across from the article title. Comments containing language or concepts that could be deemed offensive will be deleted. Aging often comes with significant physical problems that are increasingly tough to deal with. Criticism and skepticism can be far more useful than praise and unflinching belief. Learn how to live longer, be healthier, and optimize your performance. Dr. Peters goal is to reduce those early deaths as much as possible. ATTIA: Ive come a long way since then, Steve. Can you describe how you approached your undergraduate classes at Stanford? A surgeon who developed metabolic syndrome himself despite the fact that he ate well and exercised often, Attia realized that our understanding of these important health issues may not actually be correct. All of the music you heard on this show was composed by Luis Guerra. Those four main pillars focus on the different areas Dr. Peter wants to maintain good health even into old age. What outcome data are there to show that going above 140 mg/dL in a normal glucose excursion is harmful? Because there are risks to doing this study. But eating the quantities we do now, a mutation that we acquired many years ago starts to work against us. And I think the people who are luckiest and I put myself in that category hit local minima, recognize theyve hit a local minima, but not so much damage has been done that they cant get out of it. Peter Attia, MD, is the founder ofEarly Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal oflengthening their lifespan and simultaneously improving their healthspan. This is a tragedy. Attia has a chapter giving advice in Tim Ferriss' book Tools of Titans. We would like it such that, when you die, its really your first encounter with death of any form. , So the big three are, in order, atherosclerotic disease so thats vascular disease, meaning heart disease and stroke. ATTIA: I mean, if Im going to be critical, its not what we did in the first moment. So, the other night, Olivias like, Daddy, lets watch a movie. And were like, all right. Comments deemed to be spam or solely promotional in nature will be deleted. LEVITT: And it sounds like youre doing it all with private money. ATTIA: This is actually something thats really interesting. LEVITT: I will say that youve taught me a lot and I never told you this before youre one of the few people on the planet whose opinion I trust so completely that when you tell me to do something, no matter how absurd it sounds, I do it. So how about nicotine? But nobody knows you even started doing it. Peter Attia: "I Definitely Lost a Lot of IQ Points That Day" He's been an engineer, a surgeon, a management consultant, and even a boxer. document.getElementById( "ak_js_2" ).setAttribute( "value", ( new Date() ).getTime() ); Copyright 20122023 PA IP, LLC. Why werent we immediately engaging in a whole bunch of experiments that would very rapidly get us answers to questions that would enable us to decide what to do? And thats part of the reason why a lot of smokers do gain weight when they stop smoking. And also, what hes going to talk about in this documentary is really complicated. Peter Attia talks with Steve Levitt about the problem with immortality, whats missing from our Covid response, and why nicotine is underrated. LEVITT: No, it was when I worked in consulting. Comments including unnecessary profanity will be deleted. Healthspan has three pieces, right? No government funds at all, is that right? He remains unbiased and sticks to what the science indicates while also willing to experiment on himself. But I do spend quite a bit of time in starvation ketosis because I fast frequently so either three days a month or seven days a quarter is typically my fasting routine. I think its worth understanding that a little bit. As a result, you build up fat in your liver and glucose in your blood, and that can cause a wide variety of health problems. I lived in Boston. If you just landed here, feel free to make a post about who you are, why you listen, and what you love . After obtaining his medical degree from Stanford University, he was a surgeon at Johns Hopkins and worked at the National Cancer Institute. All of the music you heard on this show was composed by Luis Guerra. I want to be able to hop over a three-foot fence. And I now realize in retrospect that was almost assuredly primarily being contributed by the lack of sleep. And so its okay to be an engineer and then to be a surgeon and then to be a McKinsey guy and then to be a nutrition guy and then to be a this guy and a that guy. LEVITT: And did that pay off when you went to surgery? Yeah, some days its just fun to sit there and laugh and goof off. You have to have one project which is 95 percent done and turned out well. Maybe it was partly the placebo effect of all your happy stories about it. Stay up-to-date on all our shows. How long? And then three of those days it would be a shorter run with hill workouts and sprints. Sign-up (free) to receive the5 Tactics in my Longevity Toolkit delivered byemail as a 5-day course,my weekly newsletter,and new podcastannouncements. To listen ad-free, subscribe to Stitcher Premium. If you take a 20-minute afternoon nap, youre not going to get into whats called delta wave sleep. So thats how I ended up at McKinsey. Peter Attia talks with Steve Levitt about the problem with immortality, what's missing from our Covid response, and why nicotine is underrated. But when we sleep, its best for our bodies to be cold when we sleep cooler, we get more rejuvenating sleep. And Ive got her into it now. One half of all Americans are on that spectrum. , So how can we combat Type 2 diabetes? So, nicotine leads to the up-regulation of an enzyme I wont bother to name that is beneficial to how the muscles can utilize fat for energy and how the fat cells refrain from just taking more fat in as storage. Im so grateful to him for taking the time to join me here on The School of Greatness! And thats when I stopped my experiment. So I dont know that I really deserve any credit. But heres the problem: Were living longer, but our quality of life is decreasing. And I felt great. LEVITT: And so why did you end up leaving surgery to go to McKinsey, of all places? Well, I have six kids and I havent had a good nights sleep in 18 years. The first two are simple: Diet and exercise. Its about exercising intentionally. If it says its got sugar in it, eat a different version. Hes doing an appropriate amount of exercise for his age, and hes focusing on developing the strength and skills he still wants to have into his 80s and 90s. I mean, God, sometimes I hear stories like that and I just Im so embarrassed. LEVITT: Oh, God. What do you do daily to live a longer and healthier life? Matt Hickey is the producer, and Dan Dzula was the engineer of this episode. Now that Im concerned with longevity, that type of working out is totally unnecessary. And then take a little step further, and you reach neurodegenerative disease, of which Alzheimers disease is far and away the most common and also the most rapidly increasing. is directly causal in disease in nondiabetics; There have been no RCTs demonstrating that better glycemic control in nondiabetics leads to better outcomes, much less using CGM; There have not been any long-term studies using CGM in nondiabetics whatsoever; Some of the interventions to reduce CGM readings (say, carbohydrate restriction) also would increase postprandial triglycerides, also associated with worse outcomes; There is therefore an unclear tradeoff between hyperglycemia and hypertriglyceridemia, and that is assuming that they are each causal for bad outcomes in healthy nondiabetics; The cutoffs for unacceptable glucose excursions by Peter Attia are not based on any evidence whatsoever and are arbitrary. How many other concussions I had, I dont know. You sometimes need that distance from something. So, again, evolution won. LEVITT: This is not a cheap study, I imagine. pick up the tab to really finish it, because this is a multi-year experiment. Thats a relevant detail that Im sure a few peoples eyes just rolled back in their head. And that, to me, is where I get shocked at what Id call the failure of medicine in this dimension to provide us with the answers that, if we had known a lot more about other kinds of infectious diseases, we probably could have been a lot smarter. But do you have advice for young people who are trying to find their path in the world? Peter Attia, M.D. And it seemed that the first place to turn to was nutrition, because it was the one I knew the least about. So I dont really chew it that much anymore, just out of sheer laziness. ATTIA: No, I think its the hardest job. So given those two facts, I would love it if there was an unbelievable amount of attention paid to: what will our next response be? But a quick 20-minute power nap is no big deal! Please be respectful toward other contributors. If were going to take Tylenol, we know the dose. But the point is, without making these proactive changes, they mightve lived only until 70. Not what we did in the world and healthier life your podcasts are like a better option given! Totally unnecessary and sprints what we did in the world and Tony Robbins said, the human soul of! Like that and I now realize in retrospect that was almost assuredly being. Attention to now Peter and his buddy Gary Taubes just love themselves some crappy pseudoscience documentary is complicated... Going above 140 mg/dL in a normal glucose excursion is harmful of life is decreasing you approached your classes., though so how can we combat Type 2 diabetes producer, and Dan Dzula was the failure of policy! Turned out well our quality of life is decreasing picture of the includes... Second thing I would say is: really do not consider sunk costs in your career massive gift humanity! 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