I have seen nothing in the recent research to indicate competition for absorption between strontium and iron or magnesium. Consumers of conventionally-grown foods are at risk of strontium deficiency, which, as you will soon see, is a factor that increases our risk of osteopenia/osteoporosis as we age. Ultrasonics. My understanding is that Supplement Facts are required to list the amount of the element (in this case, strontium). You should also avoid taking it with calcium supplements or calcium-rich foods or consuming these foods 2 hours prior or 4 hours after taking the medication because the calcium can decrease the body's ability to absorb the hormone. Please give Strontium Boost a try. Ranelic acid is a synthetic chemical that belongs to the same family of toxins as benzene and polycyclic aromatic hydrocarbons (PAHs). I have a history of IBS and have avoided gluten and used probiotics which has helped my GI tract to return to normal. You just need to provide your bones with the nutrients they require to rebuild, stop doing any of the things I discuss in Your Bones that you might be doing that promote inflammation, and get a little weight bearing exercise. I was wondering what your opinion on giving dogs canned sardines in water is. Along with bone-building elements calcium and magnesium, strontium is a member of the elements in Group 2 on The Periodic Table meaning it shares some similar chemical properties. I am leaning toward taking two of the Low Dose LE K2 rather than accumulate too much of the other K vitamins in my system. I am trying to compile information on research on strontium citrate and this will greatly add to my body of information. The apatite crystals that contain strontium ions are more stable, have more regular shapes and are more resistant to stress. Obviously, this is not the case. A special form of strontium called strontium ranelate can increase bone formation and prevent bone loss when used in postmenopausal women with osteoporosis. I use AlgaeCal Plus for my supplemental calcium and vitamin K, and part of my vitamin D (I need additional vitamin D because of my genetic inheritance my vitamin D receptors dont work very well, so I need more vit D than most people), and I take Strontium Boost for my strontium. Here is the researchers conclusion for the first study: In conclusion, taken up by bone, Strontium induced no major modifications of the bone mineral at the crystal level. One of strontium's isotopes Strontium-90 has a more sinister reputation. Here are the two most recent papers I found most interesting and helpful: Hou JM, Xue Y, Lin QM. I hope this answers your question I realize I sound like a broken record here, but the point is that even though SOTI and TROPOS showed beneficial effects on bone from strontium ranelate, we can have these benefits using a natural form of strontium (like strontium citrate) without the health risks (and high financial costs) of taking the patent medication. https://www.ncbi.nlm.nih.gov/pubmed/17543560. Further increases occurred within an interval of 90-180 days, with the most recent, after 800 days, at the finger and ankle being 7 and 15 times higher than the initial baseline reading. The drug makes your bones stronger and lowers your chances of getting fractures. Of course, the elemental vs. compound difference can explain the seeming dosage discrepancy. As you likely know, rat and human absorption mechanisms are similar, albeit not equivalent. Lis thesis also very nifty I am assuming this was animal research, so results would need to be confirmed in human trials, but his suggestion that calcium will supply nutrition for bone while strontium will display synergistic effects for enhancing bone formation activity and confirmation via the finding that Oral administration of strontium fortified calcium compound significantly increased expression of IGF-I and Runx2 in bone matrix. Im now 64 and hope to be taking AlgaeCal Plus for many years to come shooting for staying here with healthy bones until Im at least 100. Dear Lara, These two excerpts from the AlgaeCals website that appear to contradict each other. Do not take AlgaeCal Plus and Strontium Boost at the same time. Try taking 150 mg of magnesium citrate along with one capsule of P-5-P (pyridoxal-5-phosphate) in the evening along with your Strontium Boost. First thing in the morning is best because if taken to late at night you might have problems falling asleep, due to the altering serotin levels. Dont know what that is from. After about 2 weeks I noticed extreme fatigue. These techniques were applied on bone mineral samples obtained from the iliac crest of male cynomolgus monkeys treated for 13 weeks with oral doses of strontium ranelate. Curzon study especially interesting to me was This effect seems to reach its optimum when concentrations of Sr at 5 to 10 mg/l with 1 mg/l of F are present in the drinking water for man. As you probably know, fluoride in excess is damaging to teeth and to bone. What is you opinion of this? A good b-complex product to take with it is B-right from Jarrow Formulas. Has anything else diet or medications or an infection, like the flu changed recently? (Having the flu can depress your stomachs ability to secrete stomach acid for a bit, so can antibiotics if youve been told to take them for any reason.) They affect the skin, liver and immune system precisely the organ systems where these ADRs caused by ranelic acid occur. I noticed a blog that mentioned the thyroid gland,also went back and read Your Bones which recommends 680 mg. Should I take only 1 capsule daily of the stronium boost instead the 3 capsules? Re the inflammation (which as you know promotes activation of osteoclasts, so we really need to get that down! If this does not help, you should see your doctor to rule out other causes of gastritis (stomach inflammation), such as H. pylori infection or problems with your gallbladder or pancreas both of which are involved in digestion (the gallbladder secretes bile, pancreas produces pancreatic enzymes), so their dysfunction can cause nausea. I could feel a pin prick in my liver or kidney. Re strontium the amount you are currently taking is very low! MATERIALS AND METHODS: The intestinal permeabilities of 14 drugs and three drug-like compounds with different absorption mechanisms in rat and human jejunum were determined by in situ intestinal perfusion. For most everyone, citrate is REALLY good for us its metabolized in the body as an alkalinizing agent in other words, it promotes an alkaline pH inside our cells. No worries it took me months to figure this out. Strontium, like calcium, incorporates into both trabecular and cortical bone, but strontium deposits almost entirely into newly forming trabecular bone, with one strontium ion substituting for less than one calcium ion out of 10 in the bone matrix. Required fields are marked *. Glucocorticoid-induced osteoporosis.Clin Exp Rheumatol. The reason 4 hours is recommended is that even if your digestion is slower than normal, you will have absorbed any calcium that was present in your meal or supplements by then. Charlotte. Hope you will let me know how your DXA turns out. Watch acid/alkali balance. That makes sense about the calcium dosage; the online label didnt say how often to take it. I applaud you for taking action to become well informed and make the best decisions you can for your own health. How is your digestion? This individual had results that were slightly under 2,000 ng/ml which, in her assessment, is over 4,000 % higher than the upper normal limit of 45.0 ng/ml. (2002). Personally, I rely upon both vitamin A, which I take in an amount equivalent to the vitamin D3 I need to take, and 2 tablespoons of Triple Power each day, to keep my inflammation down and to protect not just my bones but my overall health. Im now not certain where youre getting your information, but great I have your excellent book so I will not ask you to repeat anything from there. Stay gloriously well, Lara. Cost for the Kindle version is around $7, and I think the print version is being sold on Amazon for around $9. The only issue I have ever heard even anecdotally mentioned re MK-7 is that one woman wrote me that it gave her so much energy, she had trouble sleeping; she has to use MK-4, which clears out of the body much more rapidly than MK-7, for which reason, an effective dose of MK-4 is 45 milligrams per day! These are the 4 and 16alpha -OH compounds derived from estrogen, which are pro-inflammatory. D3 and K2 must be in balance. Ask your doctor to get tested to know your current levels and how much you need to bring your levels up to the healthy range. PMID: 15336592 DOI: 10.1016/j.bone.2004.04.026. In the past two years I have been measured to be one inch shorter. Radioactive strontium is formed in nuclear reactors or during the explosion of nuclear weapons. But in taking them separately, does strontium replace calcium in the bones? A long-term treatment with strontium ranelate in intact rats is very safe for bone and improves bone resistance by increasing bone mass and improving architecture while maintaining bone stiffness. As I explain in Your Bones, the research indicates that the MK-4 form of K2 must be taken in 3 doses of 15 millligrams each spread throughout the day in the studies, the dosage schedule was every 6-8 hours. Upon completion of this initial study, a second study was done to look at the effects of three different versions of an AlgaeCal bone-health supplement program. Strontium increases our absorption of calcium yes, calcium! I had been rebuilding bone, but slowly. I just want to give an enormous thumbs up for the great info youve here on this post. Are you ApoE4? Lara, Keep working ,impressive job! Both have been shown in the research to significantly lessen risk of falling (and thus of fractures). But I would strongly advise you NOT to use any dosage of this abnormal form of strontium! Rely on Science, not rumor. Just prefer not to take anything that may have side effects. I looked but could find no other study that has replicated these findings or reported similar findings since. As you know, shortly after maximal bone mass has been accrued (early to mid-30s), women start losing 0.5-1% of their BMD annually, a loss that accelerates to 2% or more during menopause and continues for as many as 10 years afterwards. If any of these critters are present in your digestive tract, which is extremely common, they will co-opt the citrate and use it to fuel their own activities. In monkeys killed at the end of exposure (13 or 52 weeks), Sr was taken up in a dose-dependent manner into compact and cancellous bone, with a higher content in new bone than in old bone. What about someone with coronary artery disease? The only really good food source of vitamin A is liver, which few of us consume regularly any more (and if you do eat it, PLEASE be sure to only consume organic liver!) I decided to ask you about low dose strontium to see if you had read something I hadnt or would come to the same conclusion I was beginning to. One ounce of chia seeds about 3 tablespoons will give you 176.68 milligrams of calcium. The first is a review paper looking at animal (monkey) and human studies and the second is an animal (rat) study. Great! https://www.ncbi.nlm.nih.gov/pubmed/?term=15336592 Plus, strontium is mainly incorporated onto the crystal surface of newly formed (trabecular) bone where one ion of strontium replaces less than one calcium ion out of 10. Hi David, thanks for your questions! Keep a diet diary for 4-5 days and you should be able to easily see how much calcium your diet is providing for you. If you follow the dietary recommendations in Your Bones, you will lower your blood pressure along with your risks for virtually all chronic degenerative diseases, and build healthy bones along with overall good health. 3X better proliferation of Osteoblasts than CaCO3 and Ca Citrate. 2014 Apr;61:48-54. doi: 10.1016/j.bone.2014.01.002. Hi Patricia, If you are taking 7,000 IU vit D3, then this amount of MK-7 should be adequate. My results have been excellent after 10 months of using AlgaeCal as my source of supplemental calcium, I had my DXA run. All forms of strontium and calcium have strong bone-seeking properties, and both share common transport pathways, so they compete for absorption in the intestines and for reabsorption in the kidneys. Hi Barbara delighted you are getting well informed and taking the best care of your bones (and all the rest of you if you are eating the healthy diet and following the exercise recommendations in Your Bones). Also you should know that much of what I have written about strontium ranelate is not provided by AlgaeCal and does not appear on AlgaeCals website or the AlgaeCal Community as our focus is on how to support bone health, not the adverse effects of the bone drugs. Because PTH exhibits an exaggerated response to any calcium, it is not considered a valid measurement by researchers in bone health. What you are now doing sounds just fine, although a number of other nutrients are required for optimal bone health you should also be getting adequate vitamin D3, vitamin K2, boron, magnesium and vitamin C plus a wide range of trace minerals. Epub 2014 Feb 25. It can be found in soil and seawater, and it's actually used as a supplemental treatment for osteoporosis and other bone diseases. I also use their strontium boost product its less expensive for me since I order 6 months of both at a time and get a good discount on the price, and also dont have to think about having to order something more than twice a year. However, my confusion now lies in the amount of calcium in the two tablets of AlgaeCal Plus. 6. Be the first to learn about the latest research, exclusive offers, exercises, and recipes! Delighted you are working with a receptive physician! In research studies, hair loss has never been reported as a side effect of natural strontium salts (such as the strontium citrate in Strontium Boost). I take more vitamin D now. In men, a small loss is detected in 40-year olds, which increases to a loss of about -0.8% per year into old age. [Article in Japanese] PMID: 27628553. It is best to take strontium supplements and calcium at different times of day to get the most benefit. As you can see from the references listed below, in the Niu et al. study, the exercises were conducted during short breaks from work at the office. In answer to your first question regarding the labeling on AlgaeCals calcium products, yes, they supply a little bit more than the DRI, but the DRI is considered insufficient by virtually all the experts in the field of vitamin D research. Hi Connie, Hi Shaine, The key take-away here is that natural forms of strontium significantly improve our ability to build new trabecular bone and maintain healthy (older) cortical bone a win-win for our skeletal health. You could contact them and ask them what they do to ensure their products are free of heavy metals and other contaminants. AlgaeCal Plus provides more calcium than this amount of strontium and surely with your dietary intake of calcium, you will be getting quite a bit more than 680 mg. Re Drs Best strontium if it is strontium citrate, it should be fine. I have been trying to take the Strontium Boost but it gives me headaches. As always thanks again for your insights. If I do continue on it, will this contribute to a worsening of my existing kidney disease? Even after adjusting your score down by about 10%, an increase in bone density is still an increase! Re pulsed signal therapy this also looks both safe and helpful. The reason for your headaches is not the citrate. PMID: 15329809 [PubMed indexed for MEDLINE] Free full text. This is a subtle distinction, but Im wondering if people are misinterpreting the instruction to take strontium separately. 2011 Apr;51(3):281-8. You can use this list to estimate how much calcium your diet is typically supplying each day, then subtract this amount from 1,200mg and take the remainder in the form of a calcium supplement. I quit all meds. Thyroid medications can interact with other drugs, so always take them on an empty stomach with no other medications. Strontium decreases the rate at which our brain cells release glutamate. She does the bio-est, but is expensive and scary. excellent responses to queries i would like to know in what dosages do one has to AlgaeCal Plus provides 720 mg of calcium per day (4 capsules 2 AM and 2 PM) and your diet should be giving you the remaining 380 mg of calcium you need to reach a daily intake of 1,200 mg/day. Otherwise, the medication may lose its effect. If you have a copy of Your Bones (which you can get via Amazonthey sell a Kindle version for about $7.00, so wireless delivery might be easiest for you), look at the section on Calcium and you will see a list of all the commonly eaten foods (at least in the US, Europe and other coutries with so-called western cultures, like New Zealand, Australia) that contain calcium, the typical serving size for each food and how much calcium it provides. Pregnancy or breastfeeding: Don't take without approval from your healthcare provider. It must have been something else that upset my stomach and I am now taking all the pills with no side effects. The other two Plans also used AlgaeCals plant calcium, but in differing amounts (750 mg in Plan 2, 756 mg in Plan 3), and with differing amounts of vitamin D3 ( 1,000 IU in Plan 2; 1,600 IU in Plan 3) and other bone health ingredients. Speak to our team of Bone Health Consultants Monday - Friday, 5am - 4pm PST and Saturday - Sunday, 6am to 4pm PST. Experts now believe strontium is, an essential trace mineral necessary for the optimal normal development and accretion of peak bone mass, and the sustained health of our bones.. Strontium Boost provides 680 mg of strontium citrate (not 680 mg of elemental strontium), in the 2 capsule dose. This would be 1,500 mg of calcium per day, which is greater than the 1,200 mg RDI for calcium for postmenopausal women. Is it safe to take it. I have to wait 4 hours after meal to take stontium (right) so I have to stay up late or end up getting up in the middle of the night to take strontium. I have not taken it that way and saw such a great increase in bone density. LOTS of research re vit D helping to prevent falls heres a quote from just one of the most recent papers: Discussion Vitamin D supplementation can prevent falls, particularly in the vitamin D deficient elderly. (Reference: Winzenberg T, van der Mei I, Mason RS, et al. Now this really bothers me I am 47 and cant think of not taking any calcium supplement. You do not have to be suffering from 1/2 hourly hot flushes! Dont worry about strontium taking the place of calcium in your bones. BMC Musculoskelet Disord. Aquamin (used in New Chapter) has no published studies supporting its efficacy in promoting increases in bone density. Thus, at the end of long-term SR treatment and after a period of withdrawal, Sr was taken up in a dose-dependent manner into new bone without alteration of the degree of bone mineralization and with no major modification of bone mineral at the crystal level. ( I hope you are eating lots of these vegetables like spinach, kale, Swiss chard, broccoli because they contain not only calcium but other minerals and vitamins essential for building healthy bones (e.g., vitamin K1, magnesium, boron). You might consider taking a strontium citrate supplement providing approximately 680 milligrams of elemental strontiumthis is what Strontium Boost delivers, and there are other strontium citrate supplements available that also provide this dosage. I have been taking strontium citrate for two years. Last summer (July 2011), I switched to AlgaeCal Plus as my source of supplemental calcium and to Strontium Boost for my strontium supplement. I live alone and lost my family. The key to safety long term is ensuring calcium intake from diet and supplements is at least twice that of strontium. I will check out the digestion issue. Its usually a Friday or Saturday night treat for him. It clearly explains the different strontium forms and why the natural form of strontium- strontium citrate- is beneficial (and safe) for your bones. Strontium and calcium share a common carrier system in the intestinal wall, which will. Within 3 hours, you will have digested the yogurt and absorbed the calcium in it. Thank you! I expect it may not be possible for you to ask for strontium in its natural form of strontium citrate, rather than the drug form, strontium ranelate? Since switching to AlgaeCal was the ONLY thing I changed in what I had been doing, I am now a believer. I cannot know your financial situation, but nothing is as important as your health. Drastically reduced milk as they say it becomes acidic in the body switching to rice milk, hemp and now almond. Jul 24, 2006. . Blake and GM, Fogelman I. https://www.ncbi.nlm.nih.gov/pubmed/26516910 Hope this helps, Lara, I have recently been diagnosed with coronary artery disease AND low bone mass. You will not need your former calcium supplement. That said, we understand everyone is unique and we want to ensure youre feeling your best! (Oxidative stress promotes inflammation, which then triggers osteoclasts, the specialized cells that break down bone, to spring into action.) Im on an estrogen-blocker after having had breast cancer three years ago. Yes, as you will have noted in my blog on strontium, the patented/drug version of strontium, strontium ranelate has now been conclusively shown to produce numerous side effects, at least two of which, VTE and DRESS syndrome can be fatal. Hi Sara, 350, 459-468. 223-224. Both minerals share a common carrier system in the intestinal wall, which will always choose to transport calcium rather than strontium from our digestive tract into our bloodstream. Thats what I recommend for you. Remember, supplements are just that SUPPLEMENTS, not replacements for food. This is the only study Aquamin offers on bone health. Lara I am active and healthy otherwise, on no other medication. Riedel C, Zimmermann EA, Zustin J, et al. I do this by taking Triple Power, which in addition to EPA/DHA, also contains two very powerful but safe anti-inflammatory agents: curcumin and astaxanthin. I just started taking AlgaeCal Plus and Strontium Citrate. Hope this answers your question, Lara, What is a suitable no calcium snack to have with the Strontium Citrate? We hope to hear from you! Personally, I expect to no longer be even borderline osteopenic by my next DXA (about 9 months from now) and as soon as that happens, I am going to run an n=1 trial, cut my strontium dosage in half and see how that works for me. Still, cutting back to 380 mg elemental strontium per day is reasonable at this amount, it will still be helpful for your bones. I did not know that; I did take the strontium citrate shortly after eating my breakfast cereal with almond milk, which was fortified with calcium. We are, each of us, special, unique and irreplacable. But in this paper, the results they report suggest overestimation of improvement in BMD in the spine may be ~50%. They both contain sodium, but when you connect that sodium molecule to another molecule, its actions are completely different! Thanks again for your help. Looking forward to your response. As you mentioned, certain medications (including nonsteroidal anti-inflammatory drugs like aspirin or ibuprofen) can trigger lymphocytic colitis. Wonderful that your bone density is improving! The information on the strontium/thyroid is found in the Lis thesis paper cited above. I have family sisters with ckd. Only beneficial effects for strontium citrate. How old are you? The likelihood of HCl insufficiency, which can also cause nausea, increases with age, and also occurs due to the use of acid-blocking drugs or overgrowth of a bacterium called H. pylori, which is surprisingly common. The two-capsule dose of strontium citrate = 680 mg, which provides 236 mg of elemental strontium + 440 mg of citrate. I have read several good stuff here. If you can send me the names of the companies from which you are able to purchase stronium where you are, I will look at their quality control standards and let you know which I would feel comfortable trusting. So, how can we put the data into USEFUL perspective? In contrast, no correlation was found for the expressions of metabolizing enzymes between rat and human intestine, which indicates the difference in drug metabolism and oral bioavailability in two species. Regarding your skin it is extremely unlikely that strontium is the cause of your itchy bumps or chapped-feeling skin. If as much as 11.2% of the gain in BMD is an overestimation, you multiply 1.04 x .88 to see how much is an actual increase in this case, its 0.91%. You should absolutely NOT stop taking your bone health supplements or any other vitamins or minerals before getting your DXA run! We just need to keep anything high in calcium (100 mg or more) a minimum 2 hours away from strontium to avoid an absorption interaction. I hope this answers your question and inspires you to try AlgaeCal, which significantly improved my bone density in only 10 months, so I can vouch for it personally, and this is why I am doing what I can to help get the word out about AlgaeCal. 5.0 out of 5 stars Bone Health. Our kidneys eliminate strontium far more quickly than calcium: three times as much strontium is lost in urine compared to calcium. I can only have a bone density test done every two to three years. "Know that, ma'am." "Then why are you" "Three ways to do this, ma'am." I have severe osteoporosis at age 56. Getting adequate vitamin K2 is clearly important for maintaining bone strength but not everyone can afford to get K2 from supplements and getting adequate K2 from natural foods is not easy either. Great! 2012 Jan;112:212-7. doi: 10.1016/j.envres.2011.11.005. That supplement is broken up into AM and PM formulations. This is a 2007 dissertation paper I found on Europe PubMed Central. But, in people whose digestive tracts are infected with unfriendly bacteria, such as Clostridia, citrate can be co-opted by these bactera and used to fuel their metabolism. In all three treatment groups, study participants with above average compliance had significantly greater increases in BMD compared to the losses seen in the two expected-change reference groups. Two women had to suspend training for a few weeks due to knee arthroplasty, six women due to neurological or cardiovascular problems and six women due to glaucoma surgery. Am I understanding the new bone/old bone terminology correctly here. And this applies to ANYTHING you see on the web. Hi Lara, The latest research, which I am just now writing up for medical journal articles for docs after hearing about all this at the Institute for Functional Medicines 2013 symposium, clearly shows that humans are unable to fully digest gluten; we can only break it down into indigestible peptide fragments, one of which, called gliaden, will cause not just diarrhea, but is now being shown to promote all kinds of autoimmune diseases not just celiac disease, but Hashimotos thyroiditis, multiple sclerosis, rheumatoid arthritis, even cancer. AlgaeCal has 2 in vitro and 2 human clinical trials proving its effectiveness. THANKS for catching my misspelling of Dr. Genuis although Genius would be more appropriate for his insights and accomplishments with the COMB research, and more fun (have you ever noticed the synchronicity between peoples names and their professions or accomplishments? 236 mg of elemental strontium + 440 mg of calcium in your bones %, an increase bone! Decreases the rate at which our brain cells release glutamate 2 human clinical trials proving its effectiveness competition... Which are pro-inflammatory aromatic hydrocarbons ( PAHs ) up for the great info youve here on this post list. [ PubMed indexed for MEDLINE ] free full text the inflammation ( which as you mentioned, certain medications including! With other drugs, so always take them on an estrogen-blocker after had... Dosage ; the online label didnt say how often to take strontium separately the best decisions you can your! Immune system precisely the organ systems where these ADRs caused by ranelic acid is a suitable no snack! 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Rate at which our brain cells release glutamate absorption of calcium per day, which provides 236 mg elemental! From diet and supplements is at least twice that of strontium its usually a Friday or night! Empty stomach with no other medication, to spring into action. aromatic (...