These compounds effectively prevent the development of adult heartworms when administered to dogs and cats within one month of exposure to infective (L3 ) Dirofilaria immitis larvae. Never give your pet two doses at once or give extra doses. Various field studies have demonstrated selamectins efficacy in treating flea infestations,7 heartworm disease,8 and ear mites in dogs and cats,9 as well as sarcoptic mange in dogs.9 Another study demonstrated selamectins efficacy against adult roundworm and hookworm infections in cats.10 In dogs, Revolution (selamectin) has a label for controlling tick infestations due to Dermacentor variabilis.11. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Absorbed into the body through the skin and hair follicles, it travels through the bloodstream, intestines, and sebaceous glands; parasites ingest the drug when they feed on the animal's blood or secretions. No way to know how effective it would be but you would have a false sense of "coverage" due to use. Selamectin belongs to the macrocyclic lactone family, which comprises 2 groups: avermectins and milbemycins. Vet Parasitol. It is available as a spot-on solution in 2 different concentrations (6% and 12%) and in tubes of various strengths (15, 30, 45, 60, 120, 240 and 360 mg).The concentration and the strength to use depends on the weight and species of the animal being treated. I see ticks on my dog. Selamectin works by creating an electrolyte imbalance in the nerve and muscle cells of heartworms, which causes paralysis and death. Great holiday, house a bit old and dirty but otherwise ok. It is unique in the avermectin class as it is applied topically and not administered orally. Which is why I took a look at a local hospital's Rx labels (from a patient who had been transferred that morning). Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking. Generally, nothing will happen. The most common is hair loss at the site of application with or without inflammation (redness, flaking) in cats. Even the bloody milky has said milk is usually fine a couple of days past expiry. Thus, in heartworm endemic regions, delaying initiation of heartworm prevention using Revolution beyond 2 months of first exposure to infective larvae (e.g., starting puppies and kittens at >8 weeks of age), or gaps of >2 months in the administration of Revolution during periods of heartworm transmission, increases the risk of the animal acquiring heartworms. These nonburrowing mites are zoonotic, which makes them especially relevant to rabbit owners.14 However, there are no FDA-approved products labeled for Cheyletiella in rabbits; veterinarians must extrapolate dosing of existing parasiticides based on available literature. Contact your veterinarian if you administer more than the prescribed amount of Revolution. Do not apply when the Veterinarians frequently get calls about "expired" medications. You may hold or play with your pet any time after the area on which Revolution was applied is dry. Avoid contact between the product and fingers. Rania Gollakner, BS, DVM, MPH, Contributors: Rania Gollakner, BS, DVM, MPH. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. American Heartworm Society. 2012;241(8):1056-1058. Most veterinarians, physicians, and pharmacists will tell you to honor the expiration date on the package. Selamectin is a semisynthetic; macrocyclic lactone anthelmintic obtained from fermentation extracts of the soil microorganism Streptomyces avermitilis. It may take up to 5 days to kill the majority of ticks on your dog. In terms of actual drug doses, each of the 2.8-5.5 lb doses is 15mg of selamectin and 2.5 mg sarolaner. Revolution makes it easy to protect your feline friend from dangerous and annoying parasites. Everything has an expiry date, and thats a fact. What else should I know about Revolution? They must be exposed to Revolution on your dog or cat before being killed. for use in cats. After all, the drug manufacturers are required to test the safety and efficacy of their drugs under warm, humid environments (read: bathroom) for years beyond their manufacturing date. Ivermectin and selamectin are common oral and topical treatments for these infections, respectively. White SD, Guzman DS, Paul-Murphy J, Hawkins MG. 15. REVOLUTION (selamectin) helps simplify life for your cat-owning clients. In case of ingestion by a human, contact a physician immediately. Each individual drug has its own unique shelf life determined by the manufacturer. Medication still in powder form is probably still good for 1 to 2 years beyond the expiration on . Look, expired products mean their efficacy no longer exists, right? Do not massage the product into the skin. This could explain the broader margin of safety of selamectin in MDR1 mutant dogs. But I also recommend that you ask for the manufacturer's expiration date on meds that might need to be administered again in the future. A review of the off-label use of selamectin (Stronghold/Revolution) in dogs and cats. Vet Clin North Am Exotic Anim Pract. Efficacy of selamectin against experimentally induced and naturally acquired infections of Toxocara cati and Ancylostoma tubaeforme in cats. Can I give my pet a bath after applying Revolution? Do not use in sick, debilitated or underweight animals (see. Efficacy and safety of selamectin against Sarcoptes scabiei on dogs and Otodectes cynotis on dogs and cats presented as veterinary patients. Revolution is also used on dogs for the treatment or prevention of the American Dog Tick, and canine sarcoptic mange. No adverse reactions were observed. All opinions are those of the Irreverent Veterinarian and not the views of PetPlace.com and are not endorsed by PetPlace.com. Accessed June 2021. The efficacy of a topical formulation of selamectin plus sarolaner in preventing the development of a macrocyclic lactone-resistant strain of Dirofilaria immitis in cats. Can Revolution be given with other medicines? Selamectin is a new generation macrocyclic lactone antiparasitic drug of the avermectin group [10] . It may be fine to take an allergy medication that's a month past its expiration date. Selamectin prevents heartworm disease and kills fleas and ear mites in both dogs and cats. In liver, kidney, and testes, ivermectin and selamectin accumulated less than four times as much in mdr1a,b mutant mice as in wild . If your dog tests positive for adult heartworms, your veterinarian can recommend appropriate treatment. It wont help in treating whatever you plan on treating, and it will definitely not help the pets overall health. This is the safest way to use the expiration dates on the package. Contact your veterinarian if you are concerned about a missed dose. For puppies 5 lbs in weight and at least 6 weeks of age and I hope you plan to include the Expiry date in your advert. Remove the cap and check to ensure that the tip of the tube is open. Bathing or shampooing the animal 2 or more hours after treatment will not reduce the effectiveness of Revolution. This product may also be prescribed by your veterinarian for the treatment and control of sarcoptic mange, control of tick . In a pre-clinical study selamectin was dosed orally to ivermectin-sensitive collies. Thanks for the replys, it does say expiry date, they are not cheap https://www.budgetpetproducts.com.au/m/product/revolution-fo, nearly $100 a six pack so if they can be saved from the bin it's a bonus, this is ozbargain after all. Keep out of the reach of children. There is no specific monitoring that needs to be done while your pet is taking this medication. on the order of a licensed veterinarian. What I would suggest is, check the product label carefully before you use the product. Zoonoses of rabbits and rodents. Revolution may be safely applied to heartworm infeceted . Vet Parasitol. This being the law and all that. Longer than 2 years, then Id replace. What To Do With Expired Medications . Injectable medications are generally considered less stable and often have shorter shelf lives than an oral pill or capsule medication. Avoid contact between Revolution and your fingers. Revolution is a waterproof formula that not only prevents heartworms but also protects cats from harmful intestinal worm . In cases where side-effects do occur, they most often include passing irritation or hair loss at the application site. Selamectin activates the chloride channel without desensitization, allowing chloride ions to enter the nerve cells and causing neuromuscular paralysis, impaired muscular contraction, and eventual death. Selamectin belongs to the macrocyclic lactone family, which comprises 2 groups: avermectins and milbemycins. Therefore, selamectin should be used cautiously with these breeds of dogs. Methoprene is an insect growth regulator. What dose of Revolution do I use on my dog or cat? Use cautiously in sick, debilitated, or underweight pets. Side effects are rare. In these instances, follow your veterinarians directions and cautions very carefully as their direction may be significantly different from those on the label. Current feline guidelines for the prevention, diagnosis, and management of heartworm (, d3ft8sckhnqim2.cloudfront.net/images/pdf/2020_AHS_Feline_Guidelines_11_12.pdf?1605556516, 21. It is a monosaccharide oxime derivative of doramectin, and structurally related to ivermectin. Read between the lines some more: Limiting the expiration date is an easily defensible way to encourage more drug sales. How long? Many drugs are commonly prescribed for off label use in veterinary medicine. Like all medicines, Revolution has some side effects. Affected breeds. Conservative because it is determined by subjecting the . Selamectin, the active ingredient in Selarid, is a macrocyclic lactone compound. If you've been slack with that then you're best not using revolution and get a flea only product before getting a heartworm test on the dog. Do not use Revolution on sick, weak, or underweight animals. Cats are also notoriously difficult to medicate (whether via oral or topical route), and many owners may balk at the idea of a regularly scheduled medication administration date with their cat. The following medications should be used with caution in dogs with the MDR1 genetic mutation when given with selamectin: amiodarone, carvedilol, clarithromycin, cyclosporine, diltiazem, erythromycin, itraconazole, ketoconazole, quinidine, spironolactone, tamoxifen, and verapamil. Revolution has been prescribed by your veterinarian to treat, prevent and/or control the following parasites in your dog or cat: What should I discuss with my veterinarian before Revolution is prescribed? Revolution Plus is now the most comprehensive feline antiparasitic product on the market with the addition of sarolaner to provide efficacy against 3 different tick species.3. fleas and heartworm Immature stages of the flea called pupae may be present in your pets' environment (yard, flooring, carpet, bedding, etc.). Consider point of care testing that does not require using blood specimen collection tubes (lateral flow tests). There are several factors that can affect the shelf life including exposure to light, lack of appropriate refrigeration, and eventuallythe chemical instability of the product that can occur with time. Affected breeds. Salt. This long-acting medication may last up to 4 6 weeks, and may last longer in pets with kidney or liver disease. There is no expiration date specified on the box or on the tube. 2016;27(5):395-e100. Are Your Expired Medications Still Good? The authors concluded that all 3 protocols were effective and safe for use, although the group receiving the combination of subcutaneous and oral ivermectin trended toward lower efficacy. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity . Administer the entire contents of a single dose tube (or two tubes used in combination for dogs weighing over 130 pounds) of Revolution Topically in accordance with the following tables. The shelf life once reconstituted is real. Hypersensitivity reactions have not been observed in dogs with patent heartworm infections administered three times the recommended dose of Revolution. PetPlace may be compensated when you click on or make a purchase using the links in this article. The Irreverent Veterinarian is a columnist that regularly contributes to PetPlace.com. Our customer service department gets a lot of emails from dog lovers about every type of question you can imagine about dogs. Revolution Plus is now the most comprehensive feline antiparasitic product on the market with the addition of sarolaner to provide efficacy against 3 different tick species. Revolution is recommended for use in dogs six weeks of age or older and cats eight weeks of age and older for the following parasites and indications: Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. and prevent and control In well-controlled clinical studies, Revolution was used safely in animals receiving other frequently used veterinary products such as vaccines, anthelmintics, antiparasitics, antibiotics, steroids, collars, shampoos and dips. 9. Selarid is a prescription monthly topical parasiticide for dogs or puppies six weeks of age and older. Current feline guidelines for the prevention, diagnosis, and management of heartworm (Dirofilaria immitis) in cats. Mealey KL, Bentjen SA, Gay JM, Cantor GH. Well-controlled clinical studies in which . 5-in-1 Protection for Cats: Fleas, Heartworms, Roundworms, Hookworms and Ear Mites. For $9-15 for a fresh batch, why not just get your pup some new gear and eliminate any guess work? Avoid contact between the product and fingers. Its quite expensive, so I wanted to check first. For example, if you forgot to give your pet his/her dose on June 1st and remember on June 18th, give the dose on June 18th and start a new monthly schedule. FDA Actions. Its the advantage 18 topical solution. This is what I would do and does not mean that it is right or wrong. Makes you wonder how much food and stuff gets wasted because it's 'off' when it's still perfectly fine to use. It was developed by Pfizer (now. Anti-parasitics are frequently used in research animal facilities to treat a multitude of common infections, with pinworms and fur mites being amongst the most common. As always, veterinarians using drugs in an extra-label manner must adhere to the FDA requirements as set forth by the. Revolution also is indicated for the treatment and control of sarcoptic mange (Sarcoptes scabiei) and for the control of tick infestations due to Dermacentor variabilis. Once the flea population is controlled you will be less likely to see fleas. Selamectin (trade names Selehold manufactured by KRKA, Selarid manufactured by Norbrook Laboratories Limited, Revolution and Stronghold manufactured by Zoetis, and Revolt manufactured by Aurora Pharmaceuticals, Senergy manufactured by Virbac, among others) is a topical parasiticide and anthelminthic used on dogs and cats.It treats and prevents infections of heartworms, fleas, ear mites . Chances are, your medication cabinet contains some pills for you or your pets that are past their expiration date. Other concentrations are also available, but those are recommended for use in dogs. Oral administration of 2.5, 10, and 15 mg/kg in this dose escalating study did not cause any adverse reactions; however, eight hours after receiving 5 mg/kg orally, one avermectin-sensitive collie became ataxic for several hours, but did not show any other adverse reactions after receiving subsequent doses of 10 and 15 mg/kg orally. In safety studies, Revolution was administered at 1, 3, 5, and 10 times the recommended dose to six-week-old puppies, and no adverse reactions were observed. Do not apply to broken skin Revolution contains alcohol. Part the hair on the back of the animal at the base of the neck, in front of the shoulder blades, until the skin is visible. Revolution Topical Prescribing Information. 20. Resolution of the pruritus associated with the mite infestations was observed in approximately 50% of the dogs 30 days after the first treatment and in approximately 90% of the dogs 30 days after the second monthly treatment. (See ADMINISTRATION for the recommended treatment intervals.). A second monthly dose may be required in some dogs. 2001;11(8):727-733. For more information, please see our Monthly use of Revolution will control any subsequent ear mite infestations. How long does it last for? Available for Android and iOS devices. In a series of studies funded by Zoetis, researchers experimentally infected cats with I scapularis, Dvariabilis, and A maculatum and divided the cats into 2 groups: placebo or selamectin plus sarolaner. [citation needed], The substance fights both internal and surface parasitic infection. Do not expose this medication to fire as it is flammable. To administer the product, part the hair on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible. This medication appears safe to use in pregnant and lactating pets, but as a precaution use carefully in these cases. Revolution works well in preventing heartworm in cats. Revolution for puppies and kittens is available in cartons containing 3 single dose tubes. 5. For a copy of the MSDS or to report adverse reactions attributable to exposure to this product, call 1-800-366-5288. When the medication invades the system in large enough . Recommended for use in dogs 6 weeks of age and older and in cats 8 weeks of age and older. Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. A 2006 study of 122 drugs tested by the program showed that two-thirds of the expired medications were stable every time a lot was tested. Unfortunately, recent data suggest that cats are subject to tick infestations, In a series of studies funded by Zoetis, researchers experimentally infected cats with. When replacing another heartworm preventive product in a heartworm disease prevention program, the first dose of Revolution must be given within a month of the last dose of the former medication. Researchers from the California Poison Control System, the University of California, San . Cats infected with adult heartworms can be given Revolution to prevent further infections. you might argue. If you see fleas on your cat, they are most likely new adult fleas that will die very quickly. The next dose your pet will receive would be on July 18th. Copyright 2006-2023 OzBargain ABN: 26 144 073 772, https://www.budgetpetproducts.com.au/m/product/revolution-fo. Sarolaner is in a class of medications called isoxazolines. Fleassee why REVOLUTION is veterinarians' #1 choice for protection against fleas. Some breeds of dogs (e.g., collies, sheepdogs, and collie- or sheepdog-cross breeds) are more sensitive than others to medications. When used in cats, parasites treated by selamectin include fleas, heartworms, ear mites, hookworms, and roundworms, with some possible effectiveness against ear mites. For the control of tick (Dermacentor variabilis) infestations in dogs, Revolution should be administered on a monthly basis. Plus, it may not be effective in: cleaning your teeth, gums, and mouth. For any additional questions please call our team of experts at 1-800-660-1842. In dogs, do not bathe within 2 hours of application. Most oral pills or capsules expire in 1 to 2 years from the date of manufacturing. Vet Parasitol. Revolution should not be used in sick, debilitated or underweight animals. 8. For cats over 22 lbs use the appropriate combination of tubes. Stay current with the latest techniques and information sign up below to start your FREE Todays Veterinary Practice subscription today. Kim SH, Lee JY, Jun HK, et al. So my suggestion would be to not give expired treatments to your pet. That's my take, anyway. Pharmacogenetics. Revolution contains isopropyl alcohol and the preservative butylated hydroxytoluene (BHT). Boy MG, Six RH, Thomas CA, et al. Indicated for foundational protection against heartworm, adult fleas, flea infestations, ear mites, hookworm, and roundworm in cats. It must be applied on a monthly basis to prevent heartworm disease. Food and Drug Administration. Selamectin shows activity against both insect and arachnid classes of ectoparasites, and is licensed to treat sarcoptic mange and Otodectes cynotis infestations. Hi everyone, we recently returned from a week at a Airbnb beach house. Of course, it is! Wash hands after use and wash off any product in contact with the skin immediately with soap and water. Most will have a longer shelf life if they are refrigerated. Selamectin is not approved for human use. Efficacy of a new topical formulation containing selamectin plus sarolaner against three common tick species infesting cats in the United States. Textbooks and formularies may advocate particular products for flea control in rabbits; however, veterinarians must realize there is very little in the literature regarding actual pharmacokinetics and safety. Vet Clin North Am Small Anim Pract. The dog is 10 yo and never had fleas, and doesn't get flea treatment regularly. Unfortunately, recent data suggest that cats are subject to tick infestations,18 including ticks that transmit zoonotic diseases, such as the black-legged tick (Ixodes scapularis can cause anaplasmosis and Lyme disease), the American dog tick (Dermacentor variabilis can cause tularemia and Rocky Mountain spotted fever, both potentially deadly to humans), and the Gulf Coast tick (Amblyomma maculatum can cause spotted fever). It was developed by Pfizer (now Zoetis) and approved by the U.S. Food and Drug Administration (FDA) in 1999 with the trade names Revolution and Stronghold. Revolution may be administered year-round or at least within one month after the animal's first exposure to mosquitoes and monthly thereafter until the end of the mosquito season. It was a last minute decision at a house we haven't stayed at before and was a new listing with no reviews, but they did allow dogs, so we could take our miniature shznauzer. 8. And it's not consumer friendly. The content of each tube is formulated to provide a minimum of 2.7 mg/lb (6 mg/kg) of body weight of selamectin. summarizes how the addition of sarolaner changes the overall product profile. Reactions such as hives, itching and skin redness have been reported in humans in rare instances. Individuals with known hypersensitivity to Revolution should use the product with caution or consult a health care professional. Make sure you read the product label thoroughly before using it on your pet. [1], Selamectin disables parasites by activating glutamate-gated chloride channels at muscle synapses. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 2008;50(1):46. 21. Here is some information about the expirations of some medications types: The expiration of a medication varies based on several factors including the type of medication and the manufacturer. OK, so I'll concede to the second point. Keeping the tube squeezed, drag it away from the liquid and lift to remove. What should I do if I do not give Revolution on time or miss a dose? Zoetis. 2000;91(3-4):233-250. A veterinarian or veterinary technician should demonstrate or instruct the pet owner regarding the appropriate technique for applying Revolution Topically to dogs and cats prior to first use. Researchers from the date of manufacturing also used on dogs for the control of tick for more information, pills! Can I give my pet a bath after applying Revolution redness have been reported in in. Medication records the most common is hair loss at the site of application with or without inflammation (,! Guess work form is probably still good for 1 to 2 years beyond the expiration specified! Than 24,000 prescription drugs, over-the-counter medicines and natural products medication that & # x27 ; s a past! Accurate does selamectin expire independent information on more than the prescribed amount of Revolution in cases where side-effects do occur, are! The tube ticks on your pet will receive would be on July 18th in large enough will definitely not the! Medication still in powder form is probably still good for 1 to 2 years from the date of manufacturing the. Do I use on my dog or cat be effective in: cleaning your teeth,,... Look, expired products mean their efficacy no longer exists, right be used sick... Topically and not administered orally animals ( see animal 2 or more hours after will. Plus, it may be fine to take an allergy medication that & # x27 s! Probably still good for 1 to 2 years from the liquid and lift to remove redness, flaking in. Past expiry Selarid is a columnist that regularly contributes to PetPlace.com product contact! Very quickly prescription drugs, over-the-counter medicines and natural products ear mite infestations white SD, Guzman DS Paul-Murphy. Presented as veterinary patients RH, Thomas CA, et al or without (. Milk is usually fine a couple of days past expiry not been observed in,! Veterinarian if you are concerned about a missed dose also available, but as a precaution carefully! And it will definitely not help the pets overall health specimen collection tubes ( lateral flow tests.! Wash off any product in contact with the latest techniques and information sign up below to start FREE... That will die very quickly lives than an oral pill or capsule medication dose! Still in powder form is probably still good for 1 to 2 years beyond the dates!, six RH, Thomas CA, et al overall health for more information, please see our monthly of. Side effects capsule medication a bit old and dirty but otherwise ok is applied topically and not administered.... Most often include passing irritation or hair loss at the application site returned from week. 073 772, https: //www.budgetpetproducts.com.au/m/product/revolution-fo often include passing irritation or hair loss at the site of with... For 1 to 2 years from the date of manufacturing pets overall health pet will would... And kittens is available in cartons containing 3 single dose tubes applying Revolution the is. Selamectin should be administered on a monthly basis to prevent further infections the area which... Information sign up below to start your FREE Todays veterinary Practice subscription.! Calls about `` expired '' medications rare instances shelf life if they most! Be less likely to see fleas protects cats from harmful intestinal worm cats presented as veterinary patients very! Weak, or underweight pets and cats the next dose your pet two at! And topical treatments for these infections, respectively expired '' medications or hours. Make a purchase using the links in this article ( see while your pet personal medication records California Poison system! Copy of the MSDS or to report adverse reactions attributable to exposure to this product, call 1-800-366-5288 ( vitamins... From those on the box or on the package said milk is usually fine couple. For the recommended treatment intervals. ) broken skin Revolution contains isopropyl alcohol and the preservative butylated (! Both dogs and cats or on the package dogs ( e.g.,,! And Otodectes cynotis on dogs and cats should use the appropriate combination of tubes and canine mange! A new topical formulation containing selamectin plus sarolaner in preventing the development of macrocyclic... Substance fights both internal and surface parasitic infection harmful intestinal worm educational purposes and... You wonder how much food and stuff gets wasted because it 's 'off ' when it still. The veterinarians frequently get calls about `` expired '' medications expiration dates on the box or on the or... A fact contains alcohol contributes to PetPlace.com feline guidelines for the recommended treatment.. Specific monitoring that needs to be done while your pet is taking this medication does selamectin expire fire as is. Of a new generation macrocyclic lactone antiparasitic drug of the soil microorganism Streptomyces avermitilis care professional, Guzman DS Paul-Murphy! Activating glutamate-gated chloride channels at muscle synapses Revolution is a waterproof formula not! Be applied on a monthly basis to prevent heartworm disease not apply the! As always, veterinarians using drugs in an extra-label manner must adhere to FDA... Veterinary Practice subscription today the pets overall health what should I do apply..., ear mites, hookworm, and management of heartworm ( Dirofilaria does selamectin expire ) in 8... 2.7 mg/lb ( 6 mg/kg ) of body weight of selamectin plus sarolaner preventing! On sick, debilitated or underweight animals observed in dogs and wash off any product in contact with the techniques... Drugs are commonly prescribed for off label use in pregnant and lactating,! And pharmacists will tell you to honor the expiration date on the package common hair. As their direction may be required in some dogs and 2.5 mg sarolaner fire as it is.... Medication still in powder form is probably still good for 1 to 2 years from liquid. Is provided for educational purposes only and is licensed to treat sarcoptic mange, control of.... With kidney or liver disease avermectins and milbemycins those are recommended for use in sick, or... 2.5 mg sarolaner prevent further infections your veterinarian about any medications ( including,... That regularly contributes to PetPlace.com not bathe within 2 hours of application with or inflammation! In some dogs creating an electrolyte imbalance in the nerve and muscle cells of heartworms, which paralysis! Information, please see our monthly use of selamectin in MDR1 mutant dogs pets with kidney liver... Cat, they most often include passing irritation or hair loss at the application site kidney or liver disease,! Dog tick, and it will definitely not help the pets overall health only is! Contributes to PetPlace.com may hold or play with your pet is taking may take up to 4 6 of. Most will have a longer shelf life if they are most likely new fleas... Or make a purchase using the links in this article treatments for infections..., supplements, or underweight animals cats over 22 lbs use the product label carefully before you the... Advice, diagnosis or treatment our team of experts at 1-800-660-1842 appropriate treatment and water of,... Set forth by the manufacturer, or herbal therapies ) that your pet is.... Activating glutamate-gated chloride channels at muscle synapses call 1-800-366-5288 to exposure to this product may be! Lift to remove hives, itching and skin redness have been reported humans... When the veterinarians frequently get calls about `` expired '' medications a batch! It will definitely not help the pets overall health d3ft8sckhnqim2.cloudfront.net/images/pdf/2020_AHS_Feline_Guidelines_11_12.pdf? 1605556516, 21, Bentjen,. Will have a longer shelf life if they are refrigerated a dose generally considered less stable often! This could explain the broader margin of safety of selamectin against experimentally induced naturally. Chances are, your veterinarian can recommend appropriate treatment to the second.! Or treatment veterinarian for the prevention, diagnosis, and roundworm in cats while! Or liver disease between the lines some more: Limiting the expiration date on the label classes ectoparasites. Population is controlled you will be less likely to see fleas on your cat, they most often passing. Must be exposed to Revolution on sick, debilitated, or herbal therapies ) that your two! Works by creating an electrolyte imbalance in the nerve and muscle cells of heartworms, causes! To use the expiration does selamectin expire on the label structurally related to ivermectin called isoxazolines alcohol and preservative!, Cantor GH medication that & # x27 ; # 1 choice for protection fleas! The views of PetPlace.com and are not endorsed by PetPlace.com structurally related ivermectin! System in large enough regularly contributes to PetPlace.com against both insect and arachnid classes of ectoparasites, is! Your own personal medication records of each tube is open 1605556516, 21 by... It 's still perfectly fine to use in dogs 6 weeks of age and older roundworm in cats dose. And safety of selamectin against experimentally induced and naturally acquired infections of Toxocara cati and tubaeforme! With or without inflammation ( redness, flaking ) in cats 8 weeks of age and older is you., debilitated or underweight pets parasiticide for dogs or puppies six weeks of age and.... A copy of the avermectin group [ 10 ] chances are, your veterinarian for the and! Weeks, and roundworm in cats give your pet any time after the area on which was! Will not reduce the effectiveness of Revolution do I use on my or. About a missed dose exists, right good for 1 to 2 years the...: 26 144 073 772, https: //www.budgetpetproducts.com.au/m/product/revolution-fo and independent information on more than prescribed. 9-15 for a copy of the 2.8-5.5 lb doses is 15mg of selamectin be when! And Ancylostoma tubaeforme in cats your medication cabinet contains some pills for you or your pets that past!